Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids

Abstract

A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was very short and the yields were almost quantitative.

Keywords

• fenamic acids
• fenamic acid hydrazides
• microwave irradiation
• solvent-free reaction