Targeting stromal p38MAPKalpha triggers innate-adaptive anti-tumor immunity and sensitizes metastatic breast cancer to immunotherapy

• Douglas V. Faget,
• Xianmin Luo,
• Matthew J. Inkman,
• Qihao Ren,
• Xinming Su,
• Kai Ding,
• Michael R. Waters,
• Ganesh Kumar Raut,
• Gaurav Pandey,
• Paarth B. Dodhiawala,
• Renata Ramalho-Oliveira,
• Jiayu Ye,
• Thomas Cole,
• Bhavna Murali,
• Alexander Zheleznyak,
• Monica Shokeen,
• Kurt R. Weiss,
• Joseph B. Monahan,
• Carl J. DeSelm,
• Adrian V. Lee,
• Steffi Oesterreich,
• Katherine N. Weilbaecher,
• Jin Zhang,
• David G. DeNardo,
• Sheila A. Stewart

Affiliations

Douglas V. Faget

Washington University School of Medicine, St Louis, MO, USA

Xianmin Luo

Washington University School of Medicine, St Louis, MO, USA

Matthew J. Inkman

Washington University School of Medicine, St Louis, MO, USA

Qihao Ren

Washington University School of Medicine, St Louis, MO, USA

Xinming Su

Washington University School of Medicine, St Louis, MO, USA

Kai Ding

University of Pittsburgh, Pittsburgh, PA, USA

Michael R. Waters

Washington University School of Medicine, St Louis, MO, USA

Ganesh Kumar Raut

Washington University School of Medicine, St Louis, MO, USA

Gaurav Pandey

Washington University School of Medicine, St Louis, MO, USA

Paarth B. Dodhiawala

Washington University School of Medicine, St Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA

Renata Ramalho-Oliveira

Washington University School of Medicine, St Louis, MO, USA

Jiayu Ye

Washington University School of Medicine, St Louis, MO, USA

Thomas Cole

Washington University School of Medicine, St Louis, MO, USA

Bhavna Murali

Washington University School of Medicine, St Louis, MO, USA

Alexander Zheleznyak

Washington University School of Medicine, St Louis, MO, USA

Monica Shokeen

Washington University School of Medicine, St Louis, MO, USA

Kurt R. Weiss

University of Pittsburgh, Pittsburgh, PA, USA

Joseph B. Monahan

Aclaris Therapeutics, St Louis, MO, USA

Carl J. DeSelm

Washington University School of Medicine, St Louis, MO, USA

Adrian V. Lee

University of Pittsburgh, Pittsburgh, PA, USA; Womens Cancer Research Center – UPMC Hillman Cancer Center & Magee-Womens Research Institute, Pittsburgh, PA, USA

Steffi Oesterreich

University of Pittsburgh, Pittsburgh, PA, USA; Womens Cancer Research Center – UPMC Hillman Cancer Center & Magee-Womens Research Institute, Pittsburgh, PA, USA

Katherine N. Weilbaecher

Washington University School of Medicine, St Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA

Jin Zhang

Washington University School of Medicine, St Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA

David G. DeNardo

Washington University School of Medicine, St Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA

Sheila A. Stewart

Washington University School of Medicine, St Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA