Disseminated mucormycosis in a patient with severe COVID-19 on venovenous extracorporeal membrane oxygenation: A case report
Hazuki Ito,
Ryuichiro Kakizaki,
Keisuke Harada,
Daisuke Kyuno,
Terufumi Kubo,
Naofumi Bunya,
Takehiko Kasai,
Shuji Uemura,
Eichi Narimatsu
Affiliations
Hazuki Ito
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan; Correspondence to: Department of Emergency Medicine Sapporo Medical University, 291, Minami 1-jo Nishi 16-chome, Chuo-ku, Sapporo 060-8556, Hokkaido, Japan.
Ryuichiro Kakizaki
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Keisuke Harada
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Daisuke Kyuno
Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo-ku, Sapporo, Japan
Terufumi Kubo
Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo-ku, Sapporo, Japan
Naofumi Bunya
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Takehiko Kasai
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Shuji Uemura
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Eichi Narimatsu
Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan
Background: Since the global outbreak of coronavirus disease 2019 (COVID-19), there have been several reports of mucormycosis as a secondary complication. However, the disseminated type of mucormycosis is extremely rare. Case: A 58-year-old male patient with COVID-19 started receiving venovenous extracorporeal membrane oxygenation because of severe respiratory failure. During hospitalization, intra-abdominal hemorrhage occurred and an emergency laparotomy was performed. Subsequently, the patient suffered septic shock, and part of the small intestines and the abdominal wall became necrotic. Finally, the patient died. At autopsy, he was diagnosed with disseminated mucormycosis. Conclusion: Disseminated mucormycosis should be considered in patients with COVID-19 with refractory sepsis unresponsive to broad-spectrum antimicrobial therapy.
