Communications Biology (Jan 2023)
Levofloxacin prophylaxis and parenteral nutrition have a detrimental effect on intestinal microbial networks in pediatric patients undergoing HSCT
- Marco Fabbrini,
- Federica D’Amico,
- Davide Leardini,
- Edoardo Muratore,
- Monica Barone,
- Tamara Belotti,
- Maria Luisa Forchielli,
- Daniele Zama,
- Andrea Pession,
- Arcangelo Prete,
- Patrizia Brigidi,
- Simone Rampelli,
- Marco Candela,
- Silvia Turroni,
- Riccardo Masetti
Affiliations
- Marco Fabbrini
- Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna
- Federica D’Amico
- Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna
- Davide Leardini
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Edoardo Muratore
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Monica Barone
- Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna
- Tamara Belotti
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Maria Luisa Forchielli
- Health Science and Technologies Interdepartmental Center for Industrial Research (CIRI-SDV), University of Bologna
- Daniele Zama
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Andrea Pession
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Arcangelo Prete
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Patrizia Brigidi
- Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna
- Simone Rampelli
- Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna
- Marco Candela
- Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna
- Silvia Turroni
- Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna
- Riccardo Masetti
- Pediatric Oncology and Hematology Unit “Lalla Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna
- DOI
- https://doi.org/10.1038/s42003-023-04436-7
- Journal volume & issue
-
Vol. 6,
no. 1
pp. 1 – 12
Abstract
A longitudinal characterization of the gut microbiome in 30 pediatric hematopoietic stem cell transplantation patients reveals that the combination of levofloxacin prophylaxis and parental nutrition disrupts gut microbiome networks.
