Near-atomic resolution structures of interdigitated nucleosome fibres

Zenita Adhireksan; Deepti Sharma; Phoi Leng Lee; Curt A. Davey

doi:10.1038/s41467-020-18533-2

Nature Communications (Sep 2020)

Near-atomic resolution structures of interdigitated nucleosome fibres

Zenita Adhireksan,
Deepti Sharma,
Phoi Leng Lee,
Curt A. Davey

Affiliations

Zenita Adhireksan: School of Biological Sciences, Nanyang Technological University
Deepti Sharma: School of Biological Sciences, Nanyang Technological University
Phoi Leng Lee: School of Biological Sciences, Nanyang Technological University
Curt A. Davey: School of Biological Sciences, Nanyang Technological University

DOI: https://doi.org/10.1038/s41467-020-18533-2
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Crystal structures of nucleosome fibres assembled from cohesive-ended dinucleosomes with and without linker histone reveal open zigzag conformations that are interdigitated with one another, and suggest the role that linker DNA plays in observed variable fibre configurations and packing.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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