Synthesis and crystal structure of 1-[2-(3-ethyl-2,2-dimethylcyclobutyl)acetyl]-3-phenyl thiourea

Abstract

The title compound 1-[2-(3-ethyl-2,2-dimethylcyclobutyl)acetyl]-3-phenylthiourea has been synthesized and its crystal structure was studied. The crystal belongs to triclinic system, space group P-1, a = 10.200(2) Ǻ, b = 12.395(3) Å, c = 15.679(3) Å, α = 92.99(2)o, β = 106.00(3)o, γ = 111.95(3)o, V = 1740.4(6) Å3, Z = 2, μ = 0.187 mm−1, Dc = 1.162 g/cm3, F(000) = 656, R = 0.0784, wR2 = 0.1505, formula unit C17H24N2OS. The title compound has a fragment of 2,2-dimethylcyclobutane and its conformation represents semi-chair. The intermolecular and intramolecular hydrogen bonds are revealed.DOI: http://dx.doi.org/10.4314/bcse.v27i1.13

Keywords

• Synthesis
• Single crystal X-ray diffraction
• Crystal structure
• 2‚2-Dimethylcyclobutane