Prolonged treatment of combined oral contraceptive: a focus on the prevention of inflammatory diseases of the pelvic organs

Abstract

The article presents data on preventive effects of combined oral contraceptives (COCs) with respect to the risks of inflammatory diseases of the pelvic organs (pelvic inflammatory disease - PID), complemented by modern ideas about the influence of COCs on the state of cervicovaginal lavage, depending on the secretion of antimicrobial peptides from the phase of the menstrual cycle and the use of COCs. The data meta-analysis to reduce the recurrence of bacterial vaginosis in patients receiving COCs, the justification of the preventive effect of the prolonged mode of Yaz® intake in a flex cartridge for PID in women in need of contraception is given.

Keywords

• combined oral contraceptives
• inflammatory diseases of the pelvic organs
• bacterial vaginosis
• ethinyl estradiol
• drospirenone