The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant <em>Hyptis verticillata</em>, and NMR Characterization of Hyptoside

Abstract

Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of <em>Hyptis</em><em> verticillata</em>.

Keywords

• ATL
• bioassay-guided isolation
• S1T
• growth inhibitor
• lignan
• NMR
• structure