Медицинская иммунология (Jul 2014)

FEATURES OF CD34+ CELL KINETICS IN CHILDREN WITH DIFFERENT KINDS OF INFLAMMATION

  • I. I. Dolgushin,
  • M. V. Peshikova,
  • R. K. Babik,
  • S. I. Malakhova,
  • E. V. Zhukovskaya

DOI
https://doi.org/10.15789/1563-0625-2010-4-5-319-324
Journal volume & issue
Vol. 12, no. 4-5
pp. 319 – 324

Abstract

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Characteristics of CD34+ cells mobilization were studied in children suffering with various diseases, like as their dependence on type and extent of inflammatory response. It was revealed that the children with signs of systemic inflammatory response syndrome exhibit a significant increase of absolute content and percentage of circulating CD34+ cells, whereas children with frequent infections, and with clinical signs of allergy during recurrence of their chronic allergic disease showed a significant decrease in CD34+ cell percentage. Meanwhile, children with allergoses, and those with common recurrent infectious states did not reveal any deviations in CD34+ cells from normal values.

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