Common Variable Immunodeficiency and Type 1 Diabetes Mellitus in a 19-year-old Filipino Male with Alopecia Universalis

Abstract

A 19-year-old Filipino male presents with recurrent respiratory tract symptoms every 4 to 5 months since childhood and sudden onset of diabetes type 1 with ketoacidosis. He had patchy hair loss which started at 7 years old, and was diagnosed with alopecia universalis. Thyroid antibodies and 21-hydroxylase antibody were normal. Common Variable Immunodeficiency with Polyglandular Autoimmune Syndrome IV was considered. The patient is on monthly intravenous immunoglobulin therapy and basal bolus insulin regimen.