State of antioxidant blood system at physiological pregnancy and pregnancy complicated with bleeding

Abstract

The task of our investigation was the analysis of enzyme activity of antioxidant defense in women blood at physiological pregnancy and pregnancy complicated with hypertension. It was established that hyper production of hydrogen peroxide and glutathione peroxidase activation at physiological pregnancy improved microcirculation due to vasodilatation effect of hydrogen peroxide. It was established that activation of superoxiddysmutase and myeloperoxidase at pregnancy complicated with hypertension developed endothelial dysfunction owing to citotoxic effects of hydrogen peroxide.

Keywords

• беременность
• гипертоническая болезнь
• антиоксидантная защита
• antioxidant defense
• pregnancy
• hypertension