Nature Communications (Nov 2016)

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

  • Maria Pelliccia,
  • Patrizia Andreozzi,
  • Jayson Paulose,
  • Marco D’Alicarnasso,
  • Valeria Cagno,
  • Manuela Donalisio,
  • Andrea Civra,
  • Rebecca M. Broeckel,
  • Nicole Haese,
  • Paulo Jacob Silva,
  • Randy P. Carney,
  • Varpu Marjomäki,
  • Daniel N. Streblow,
  • David Lembo,
  • Francesco Stellacci,
  • Vincenzo Vitelli,
  • Silke Krol

DOI
https://doi.org/10.1038/ncomms13520
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 7

Abstract

Read online

Keeping viral vaccines cold from the manufacturers to patients is problematic and costly. Here, Krol and others show additives that can significantly improve at very low concentrations the storage of adenovirus type 5 at ambient and elevated temperature.