Cortical Epandimoma with Extention to Thalamus

Abstract

Ependymomas are glial tumors originate from ependymal cells lining the ventricles and the central canal of the spinal cord. Two thirds of ependymomas arise in the infratentorial or intraventricles and one-third are detected in supratentorial area. However supratentorial "cortical" ependymomas are very uncommon. Ependymomas are usually infratentorial, intraventricular tumor, including 2–9% of all central nervous system tumors. We present a unique case of an anaplastic cortical ependymoma in a 48-year-old man. The patient presented with transient amnesia and right weakness and seizure. This tumor was located in the left parieto-occipital region with extension to corpus callosum and thalamus. Microscopy and immunohistochemistry showed grade III differentiation ependymoma.