Frontiers in Pediatrics (Aug 2023)
Evaluation of nutritional status in pediatric intensive care unit patients: the results of a multicenter, prospective study in Turkey
- Merve Misirlioglu,
- Dincer Yildizdas,
- Faruk Ekinci,
- Ozden Ozgur Horoz,
- Gokhan Tumgor,
- Ahmet Yontem,
- Mehmet Nur Talay,
- Murat Kangin,
- Erennur Tufan,
- Selman Kesici,
- Nazik Yener,
- Hatice Elif Kinik Kaya,
- Merve Havan,
- Ali Tunc,
- Nihal Akçay,
- Esra Sevketoglu,
- Fatih Durak,
- Aysenur Ozel Dogruoz,
- Serhan Ozcan,
- Oktay Perk,
- Muhterem Duyu,
- Merve Boyraz,
- Mutlu Uysal Yazici,
- Zeynelabidin Ozturk,
- Mehmet Çeleğen,
- Aysegul Bukulmez,
- Ebru Kacmaz,
- Ener Cagri Dinleyici,
- Oguz Dursun,
- Alper Koker,
- Suleyman Bayraktar,
- Mey Talip Petmezci,
- Aygul Nabaliyeva,
- Hasan Agin,
- Pinar Hepduman,
- Emine Akkuzu,
- Tanil Kendirli,
- Hasan Ozen,
- Sevgi Topal,
- Çağlar Ödek,
- Murat Ozkale,
- Yasemin Ozkale,
- Gürkan Atay,
- Seher Erdoğan,
- Capan Konca,
- Guler Yapici,
- Gazi Arslan,
- Tolga Besci,
- Resul Yilmaz,
- Meltem Gumus,
- Arzu Oto,
- Tahir Dalkiran,
- Mehmet Mercan,
- Yasemin Çoban,
- Sevcan Ipek,
- Sukru Gungor,
- Ali Ertug Arslankoylu,
- Mehmet Alakaya,
- Ferhat Sari,
- Aylin Yucel,
- Abdullah Yazar
Affiliations
- Merve Misirlioglu
- Department of Pediatric Intensive Care, Faculty of Medicine, Mersin University, Mersin, Türkiye
- Dincer Yildizdas
- Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Türkiye
- Faruk Ekinci
- Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Türkiye
- Ozden Ozgur Horoz
- Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Türkiye
- Gokhan Tumgor
- Department of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Cukurova University, Adana, Türkiye
- Ahmet Yontem
- Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Türkiye
- Mehmet Nur Talay
- Department of Pediatrics, Health Sciences University, Gazi Yasargil Training and Research Hospital, Diyarbakir, Türkiye
- Murat Kangin
- Department of Pediatric Intensive Care, Faculty of Medicine, Medipol University, Istanbul, Türkiye
- Erennur Tufan
- Department of Pediatric Intensive Care, Faculty of Medicine, Hacettepe University, Ankara, Türkiye
- Selman Kesici
- Department of Pediatric Intensive Care, Faculty of Medicine, Hacettepe University, Ankara, Türkiye
- Nazik Yener
- Department of Pediatric Intensive Care, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Türkiye
- Hatice Elif Kinik Kaya
- Department of Pediatric Intensive Care, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Türkiye
- Merve Havan
- Department of Pediatric Intensive Care, Mersin City Training and Research Hospital, Mersin, Türkiye
- Ali Tunc
- Department of Pediatrics, Mersin City Training and Research Hospital, Mersin, Türkiye
- Nihal Akçay
- 0Department of Pediatric Intensive Care, University of Health Sciences Bakirkoy, Dr. Sadi Konuk Training and Research Hospital, İstanbul, Türkiye
- Esra Sevketoglu
- 0Department of Pediatric Intensive Care, University of Health Sciences Bakirkoy, Dr. Sadi Konuk Training and Research Hospital, İstanbul, Türkiye
- Fatih Durak
- 1Department of Pediatric Intensive Care, İzmir Health Sciences University, Tepecik Training and Research Hospital, İzmir, Türkiye
- Aysenur Ozel Dogruoz
- 1Department of Pediatric Intensive Care, İzmir Health Sciences University, Tepecik Training and Research Hospital, İzmir, Türkiye
- Serhan Ozcan
- 2Department of Pediatric Intensive Care, Ankara City Hospital, Ankara, Türkiye
- Oktay Perk
- 2Department of Pediatric Intensive Care, Ankara City Hospital, Ankara, Türkiye
- Muhterem Duyu
- 3Department of Pediatric Intensive Care, Medeniyet University, Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Türkiye
- Merve Boyraz
- 3Department of Pediatric Intensive Care, Medeniyet University, Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Türkiye
- Mutlu Uysal Yazici
- 4Department of Pediatric Intensive Care, Health Sciences University Ankara, Dr. Sami Ulus Obstetrics Child Health and Diseases Training and Research Hospital, Ankara, Türkiye
- Zeynelabidin Ozturk
- 4Department of Pediatric Intensive Care, Health Sciences University Ankara, Dr. Sami Ulus Obstetrics Child Health and Diseases Training and Research Hospital, Ankara, Türkiye
- Mehmet Çeleğen
- 5Department of Pediatric Intensive Care, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye
- Aysegul Bukulmez
- 6Department of Pediatric Gastroenterology, Faculty of Medicine, Hepatology and Nutrition, Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye
- Ebru Kacmaz
- 7Department of Pediatric Intensive Care, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Türkiye
- Ener Cagri Dinleyici
- 7Department of Pediatric Intensive Care, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Türkiye
- Oguz Dursun
- 8Department of Pediatric Intensive Care, Faculty of Medicine, Akdeniz University, Antalya, Türkiye
- Alper Koker
- 8Department of Pediatric Intensive Care, Faculty of Medicine, Akdeniz University, Antalya, Türkiye
- Suleyman Bayraktar
- 9Department of Pediatric Intensive Care, Sultangazi Haseki Training and Research Hospital, Istanbul, Türkiye
- Mey Talip Petmezci
- 0Department of Pediatric Intensive Care, Prof. Dr. Cemil Tascıoglu City Hospital, Istanbul, Türkiye
- Aygul Nabaliyeva
- 0Department of Pediatric Intensive Care, Prof. Dr. Cemil Tascıoglu City Hospital, Istanbul, Türkiye
- Hasan Agin
- 1Department of Pediatric Intensive Care, University of Health Sciences Izmir, Dr. Behcet Uz Child Diseases and Surgery Training and Research Hospital, Izmir, Türkiye
- Pinar Hepduman
- 1Department of Pediatric Intensive Care, University of Health Sciences Izmir, Dr. Behcet Uz Child Diseases and Surgery Training and Research Hospital, Izmir, Türkiye
- Emine Akkuzu
- 2Department of Pediatric Intensive Care, Isparta City Hospital, Isparta, Türkiye
- Tanil Kendirli
- 3Department of Pediatric Intensive Care, Faculty of Medicine, Ankara University, Ankara, Türkiye
- Hasan Ozen
- 3Department of Pediatric Intensive Care, Faculty of Medicine, Ankara University, Ankara, Türkiye
- Sevgi Topal
- 4Department of Pediatric Intensive Care, Erzurum Regional Training and Research Hospital, ErzurumTürkiye
- Çağlar Ödek
- 5Department of Pediatric Intensive Care, Faculty of Medicine, Uludag University, Bursa, Türkiye
- Murat Ozkale
- 6Department of Pediatric Intensive Care, Faculty of Medicine, Baskent University, Adana Dr Turgut Noyan Teaching and Medical Research Center, Adana, Türkiye
- Yasemin Ozkale
- 6Department of Pediatric Intensive Care, Faculty of Medicine, Baskent University, Adana Dr Turgut Noyan Teaching and Medical Research Center, Adana, Türkiye
- Gürkan Atay
- 7Department of Pediatric Intensive Care, Umraniye Training and Research Hospital, Istanbul, Türkiye
- Seher Erdoğan
- 7Department of Pediatric Intensive Care, Umraniye Training and Research Hospital, Istanbul, Türkiye
- Capan Konca
- 8Department of Pediatric Intensive Care, Adiyaman Training and Research Hospital, Adiyaman, Türkiye
- Guler Yapici
- 8Department of Pediatric Intensive Care, Adiyaman Training and Research Hospital, Adiyaman, Türkiye
- Gazi Arslan
- 9Department of Pediatric Intensive Care, Faculty of Medicine, Dokuz Eylul University, Izmir, Türkiye
- Tolga Besci
- 9Department of Pediatric Intensive Care, Faculty of Medicine, Dokuz Eylul University, Izmir, Türkiye
- Resul Yilmaz
- 0Department of Pediatric Intensive Care, Faculty of Medicine, Selcuk University, Konya, Türkiye
- Meltem Gumus
- 1Department of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Selcuk University, Konya, Türkiye
- Arzu Oto
- 2Department of Pediatric Intensive Care, University of Health Sciences Bursa High Specialization Hospital, Bursa, Türkiye
- Tahir Dalkiran
- 3Department of Pediatric Intensive Care, Necip Fazil City Hospital, Kahramanmaras, Türkiye
- Mehmet Mercan
- 4Department of Pediatrics, Necip Fazil City Hospital, Kahramanmaras, Türkiye
- Yasemin Çoban
- 5Department of Pediatric Intensive Care, Faculty of Medicine, Mugla University, Mugla, Türkiye
- Sevcan Ipek
- 6Department of Pediatric Intensive Care, Faculty of Medicine, Sutcu Imam University, Kahramanmaras, Türkiye
- Sukru Gungor
- 7Department of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Sutcu Imam University, Kahramanmaras, Türkiye
- Ali Ertug Arslankoylu
- Department of Pediatric Intensive Care, Faculty of Medicine, Mersin University, Mersin, Türkiye
- Mehmet Alakaya
- Department of Pediatric Intensive Care, Faculty of Medicine, Mersin University, Mersin, Türkiye
- Ferhat Sari
- 8Department of Pediatric Intensive Care, Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Türkiye
- Aylin Yucel
- 9Department of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Necmettin Erbakan University Meram, Konya, Türkiye
- Abdullah Yazar
- 0Department of Pediatric Intensive Care, Faculty of Medicine, Necmettin Erbakan University Meram, Konya, Türkiye
- DOI
- https://doi.org/10.3389/fped.2023.1179721
- Journal volume & issue
-
Vol. 11
Abstract
IntroductionMalnutrition is defined as a pathological condition arising from deficient or imbalanced intake of nutritional elements. Factors such as increasing metabolic demands during the disease course in the hospitalized patients and inadequate calorie intake increase the risk of malnutrition. The aim of the present study is to evaluate nutritional status of patients admitted to pediatric intensive care units (PICU) in Turkey, examine the effect of nutrition on the treatment process and draw attention to the need for regulating nutritional support of patients while continuing existing therapies.Material and MethodIn this prospective multicenter study, the data was collected over a period of one month from PICUs participating in the PICU Nutrition Study Group in Turkey. Anthropometric data of the patients, calorie intake, 90-day mortality, need for mechanical ventilation, length of hospital stay and length of stay in intensive care unit were recorded and the relationship between these parameters was examined.ResultsOf the 614 patients included in the study, malnutrition was detected in 45.4% of the patients. Enteral feeding was initiated in 40.6% (n = 249) of the patients at day one upon admission to the intensive care unit. In the first 48 h, 86.82% (n = 533) of the patients achieved the target calorie intake, and 81.65% (n = 307) of the 376 patients remaining in the intensive care unit achieved the target calorie intake at the end of one week. The risk of mortality decreased with increasing upper mid-arm circumference and triceps skin fold thickness Z-score (OR = 0.871/0.894; p = 0.027/0.024). The risk of mortality was 2.723 times higher in patients who did not achieve the target calorie intake at first 48 h (p = 0.006) and the risk was 3.829 times higher in patients who did not achieve the target calorie intake at the end of one week (p = 0.001). The risk of mortality decreased with increasing triceps skin fold thickness Z-score (OR = 0.894; p = 0.024).ConclusionTimely and appropriate nutritional support in critically ill patients favorably affects the clinical course. The results of the present study suggest that mortality rate is higher in patients who fail to achieve the target calorie intake at first 48 h and day seven of admission to the intensive care unit. The risk of mortality decreases with increasing triceps skin fold thickness Z-score.
Keywords