Nature Communications (Nov 2018)

Long term but not short term exposure to obesity related microbiota promotes host insulin resistance

  • Kevin P. Foley,
  • Soumaya Zlitni,
  • Emmanuel Denou,
  • Brittany M. Duggan,
  • Rebecca W. Chan,
  • Jennifer C. Stearns,
  • Jonathan D. Schertzer

Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15


Read online

Gut microbiota impact host metabolism and gut microbiome composition reflects dietary habits. Here the authors show that, in animals fed obesogenic diets, changes in gut microbiota precede changes in glucose homeostasis. Importantly, long term exposure of the host to the changed microbiota is required to impair glucose homeostasis.