IEEE Access (Jan 2021)

U-Net and Its Variants for Medical Image Segmentation: A Review of Theory and Applications

  • Nahian Siddique,
  • Sidike Paheding,
  • Colin P. Elkin,
  • Vijay Devabhaktuni

DOI
https://doi.org/10.1109/ACCESS.2021.3086020
Journal volume & issue
Vol. 9
pp. 82031 – 82057

Abstract

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U-net is an image segmentation technique developed primarily for image segmentation tasks. These traits provide U-net with a high utility within the medical imaging community and have resulted in extensive adoption of U-net as the primary tool for segmentation tasks in medical imaging. The success of U-net is evident in its widespread use in nearly all major image modalities, from CT scans and MRI to X-rays and microscopy. Furthermore, while U-net is largely a segmentation tool, there have been instances of the use of U-net in other applications. Given that U-net’s potential is still increasing, this narrative literature review examines the numerous developments and breakthroughs in the U-net architecture and provides observations on recent trends. We also discuss the many innovations that have advanced in deep learning and discuss how these tools facilitate U-net. In addition, we review the different image modalities and application areas that have been enhanced by U-net.

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