Protective effects of an mRNA vaccine candidate encoding H5HA clade 2.3.4.4b against the newly emerged dairy cattle H5N1 virus

• Shiho Chiba,
• Maki Kiso,
• Shinya Yamada,
• Kazuhiko Someya,
• Yoshikuni Onodera,
• Aya Yamaguchi,
• Satoko Matsunaga,
• Nao Jounai,
• Seiya Yamayoshi,
• Fumihiko Takeshita,
• Yoshihiro Kawaoka

Affiliations

Shiho Chiba

Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, 53711, USA; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan

Maki Kiso

Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan

Shinya Yamada

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Kazuhiko Someya

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Yoshikuni Onodera

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Aya Yamaguchi

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Satoko Matsunaga

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Nao Jounai

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Seiya Yamayoshi

Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, 162-8655, Japan

Fumihiko Takeshita

Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan

Yoshihiro Kawaoka

Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, 53711, USA; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, 162-8655, Japan; Corresponding author. 575 Science Drive, Madison, WI, 53711, USA.