Hemorrhagic Fever With Renal Syndrome in Vladivostok City, Russia

Liudmila N. Yashina; John Hay; Natalia A. Smetannikova; Tatiana V. Kushnareva; Olga V. Iunikhina; Galina G. Kompanets

doi:10.3389/fpubh.2021.620279

Frontiers in Public Health (Feb 2021)

Hemorrhagic Fever With Renal Syndrome in Vladivostok City, Russia

Liudmila N. Yashina,
John Hay,
Natalia A. Smetannikova,
Tatiana V. Kushnareva,
Olga V. Iunikhina,
Galina G. Kompanets

Affiliations

Liudmila N. Yashina: Department of Genomic Research, State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Russia
John Hay: Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States
Natalia A. Smetannikova: Department of Genomic Research, State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Russia
Tatiana V. Kushnareva: Department of Microbiology and Virology, Pacific State Medical University, Vladivostok, Russia
Olga V. Iunikhina: Laboratory of Experimental Virology, Somov Institute of Epidemiology and Microbiology, Vladivostok, Russia
Galina G. Kompanets: Laboratory of Experimental Virology, Somov Institute of Epidemiology and Microbiology, Vladivostok, Russia

DOI: https://doi.org/10.3389/fpubh.2021.620279
Journal volume & issue: Vol. 9

Abstract

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Hemorrhagic fever with renal syndrome (HFRS) is a public health problem in Vladivostok city, Russia. From 1997 to 2019, a study of hantaviruses in Norway rats (Rattus norvegicus), a natural reservoir of Seoul virus (SEOV), and in HFRS patients was conducted. We demonstrated the presence of SEOV in the local population of Norway rats and detected SEOV in 10, Amur virus (AMRV) in 4 and Hantaan virus (HTNV) in 1 out of 15 HFRS patients. Genetic analysis based on partial S, M and L segment sequences revealed that the Russian SEOV strains were related most closely to strains from Cambodia and Vietnam. We postulate that the SEOV strains found in the port city of Vladivostok have been spread from South-East Asia as a result of distribution of rats during standard shipping trade activities. Moreover, we suggest that city residents may have acquired AMRV and HTNV infection during visits to rural areas.

Published in Frontiers in Public Health

ISSN: 2296-2565 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Public aspects of medicine
Website: https://www.frontiersin.org/journals/public-health

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