Arquivos de Neuro-Psiquiatria (Jul 2015)

Chronic pain relief after the exposure of nitrous oxide during dental treatment: longitudinal retrospective study

  • Francisco Moreira Mattos Júnior,
  • Rafael Villanova Mattos,
  • Manoel Jacobsen Teixeira,
  • Silvia Regina Dowgan Tesseroli de Siqueira,
  • Jose Tadeu Tesseroli de Siqueira

DOI
https://doi.org/10.1590/0004-282x20150061
Journal volume & issue
Vol. 73, no. 7
pp. 578 – 581

Abstract

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The objective was to investigate the effect of nitrous/oxygen in chronic pain. Seventy-seven chronic pain patients referred to dental treatment with conscious sedation with nitrous oxide/oxygen had their records included in this research. Data were collected regarding the location and intensity of pain by the visual analogue scale before and after the treatment. Statistical analysis was performed comparing pre- and post-treatment findings. It was observed a remarkable decrease in the prevalence of pain in this sample (only 18 patients still had chronic pain, p < 0.001) and in its intensity (p < 0.001). Patients that needed fewer sessions received higher proportions of nitrous oxide/oxygen. Nitrous oxide may be a tool to be used in the treatment of chronic pain, and future prospective studies are necessary to understand the underlying mechanisms and the effect of nitrous oxide/oxygen in patients according to the pain diagnosis and other characteristics.

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