Indian Journal of Pathology and Microbiology (Jan 2022)

Perinatal and Fetal Autopsies in Neuropathology: How I do it

  • Ram Narayan Das,
  • Bappa Mandal,
  • Mou Das,
  • Kaushik Sil,
  • Suchandra Mukherjee,
  • Uttara Chatterjee

DOI
https://doi.org/10.4103/ijpm.ijpm_977_21
Journal volume & issue
Vol. 65, no. 5
pp. 207 – 217

Abstract

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Fetal and perinatal autopsies are useful to identify the accurate cause of death and in the process recognize disorders which may require counselling for future pregnancies. Abnormalities of the CNS are an important cause of fetal loss and perinatal deaths. Most of these are structural abnormalities of the CNS, however a smaller portion show changes pertaining to prematurity, infections and even congenital tumors. In this review we evaluate CNS abnormalities of the fetus and the newborn as detected in autopsy series. We also describe our experience in a tertiary care hospital with a specialized neonatology unit over the last 8 years and discuss some of the newer methods like virtual autopsy.

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