Lithium Niobate Perovskite as the Support for Silver Nanoparticles for Non-Enzymatic Electrochemical Detection of Glucose
Claudia Ivone Piñón-Balderrama,
Atenea Manríquez-Tristán,
María Cristina Maldonado-Orozco,
Claudia Alejandra Hernández-Escobar,
Simón Yobanny Reyes-López,
León Francisco Espinosa-Cristobal,
Erasto Armando Zaragoza-Contreras
Affiliations
Claudia Ivone Piñón-Balderrama
CONAHCYT-CIMAV, Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, Chihuahua 31136, Chihuahua, Mexico
Atenea Manríquez-Tristán
Faculty of Engineering, Universidad Autónoma de Chihuahua, Circuito Número I s/n, Nuevo Campus Universitario, Nte. 2, Chihuahua 31125, Chihuahua, Mexico
María Cristina Maldonado-Orozco
Faculty of Engineering, Universidad Autónoma de Chihuahua, Circuito Número I s/n, Nuevo Campus Universitario, Nte. 2, Chihuahua 31125, Chihuahua, Mexico
Claudia Alejandra Hernández-Escobar
Centro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial, Chihuahua 31136, Chihuahua, Mexico
Simón Yobanny Reyes-López
Institute of Biomedical Sciences, Universidad Autónoma de Ciudad Juárez, Envolvente del PRONAF and Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico
León Francisco Espinosa-Cristobal
Institute of Biomedical Sciences, Universidad Autónoma de Ciudad Juárez, Envolvente del PRONAF and Estocolmo s/n, Ciudad Juárez 32310, Chihuahua, Mexico
Erasto Armando Zaragoza-Contreras
Centro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial, Chihuahua 31136, Chihuahua, Mexico
Lithium niobate perovskite and silver nanoparticle-based nanocomposites (LNB:AgNPs) were explored for developing an electrochemical glucose sensor. The perovskite to silver nanoparticle ratios investigated were 4:1, 1:1, 1:2, 2:1, and 1:4. Among these, the 4:1 ratio, with the lowest silver content, demonstrated the most stable performance during glucose quantification via amperometry. The sensor’s response was evaluated measuring the current at a fixed potential of 0.7 V following the injection of 1 mM glucose with each addition. The calibration curve obtained from the recorded data exhibited a linear response within the 1 to 15 mM glucose concentration range, achieving a sensitivity of 2 μA/mM, a high correlation coefficient (R2 = 0.997), and a limit of detection (LOD) of 0.5 µM. The LNB4:1AgNP composite allowed taking advantage of the unique properties of both components in a balanced manner, maximizing the sensor performance in practical applications.
