Diagnostics (Jul 2021)

Walk Your Talk: Real-World Adherence to Guidelines on the Use of MRI in Multiple Sclerosis

  • Mario Tortora,
  • Mario Tranfa,
  • Anna Chiara D’Elia,
  • Giuseppe Pontillo,
  • Maria Petracca,
  • Alessandro Bozzao,
  • Ferdinando Caranci,
  • Amedeo Cervo,
  • Mirco Cosottini,
  • Andrea Falini,
  • Marcello Longo,
  • Renzo Manara,
  • Mario Muto,
  • Michele Porcu,
  • Luca Roccatagliata,
  • Alessandra Todeschini,
  • Luca Saba,
  • Arturo Brunetti,
  • Sirio Cocozza,
  • Andrea Elefante

DOI
https://doi.org/10.3390/diagnostics11081310
Journal volume & issue
Vol. 11, no. 8
p. 1310

Abstract

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(1) Although guidelines about the use of MRI sequences for Multiple Sclerosis (MS) diagnosis and follow-up are available, variability in acquisition protocols is not uncommon in everyday clinical practice. The aim of this study was to evaluate the real-world application of MS imaging guidelines in different settings to clarify the level of adherence to these guidelines. (2) Via an on-line anonymous survey, neuroradiologists (NR) were asked about MRI protocols and parameters routinely acquired when MS patients are evaluated in their center, both at diagnosis and follow-up. Furthermore, data about report content and personal opinions about emerging neuroimaging markers were also retrieved. (3) A total of 46 participants were included, mostly working in a hospital or university hospital (80.4%) and with more than 10 years of experience (47.9%). We found a relatively good adherence to the suggested MRI protocols regarding the use of T2-weighted sequences, although almost 10% of the participants routinely acquired 2D sequences with a slice thickness superior to 3 mm. On the other hand, a wider degree of heterogeneity was found regarding gadolinium administration, almost routinely performed at follow-up examination (87.0% of cases) in contrast with the current guidelines, as well as a low use of a standardized reporting system (17.4% of cases). (4) Although the MS community is getting closer to a standardization of MRI protocols, there is still a relatively wide heterogeneity among NR, with particular reference to contrast administration, which must be overcome to guarantee an adequate quality of patients’ care in MS.

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