World Journal of Surgical Oncology (Apr 2022)

Circ_0047921 acts as the sponge of miR-1287-5p to stimulate lung cancer progression by regulating proliferation, migration, invasion, and glycolysis of lung cancer cells

  • Yuehua Xiao,
  • Shequn Gu,
  • Wenxiu Yao,
  • Ling Qin,
  • Jihui Luo

DOI
https://doi.org/10.1186/s12957-021-02466-1
Journal volume & issue
Vol. 20, no. 1
pp. 1 – 13

Abstract

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Highlights 1. Circ_0047921 was upregulated in lung cancer tissues and cells. 2. Circ_0047921/miR-1287-5p/LARP1 axis played a key role in proliferation, migration, invasion, EMT and glycolysis of lung cancer cells. 3. Circ_0047921 regulated LARP1 by sponging miR-1287-5p in lung cancer.

Keywords