Recent Progress on Bioinspired Antibacterial Surfaces for Biomedical Application
Xiao Yang,
Wei Zhang,
Xuezhi Qin,
Miaomiao Cui,
Yunting Guo,
Ting Wang,
Kaiqiang Wang,
Zhenqiang Shi,
Chao Zhang,
Wanbo Li,
Zuankai Wang
Affiliations
Xiao Yang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Wei Zhang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Xuezhi Qin
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Miaomiao Cui
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Yunting Guo
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Ting Wang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Kaiqiang Wang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Zhenqiang Shi
CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
Chao Zhang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Wanbo Li
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Zuankai Wang
Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China
Surface bacterial fouling has become an urgent global challenge that calls for resilient solutions. Despite the effectiveness in combating bacterial invasion, antibiotics are susceptible to causing microbial antibiotic resistance that threatens human health and compromises the medication efficacy. In nature, many organisms have evolved a myriad of surfaces with specific physicochemical properties to combat bacteria in diverse environments, providing important inspirations for implementing bioinspired approaches. This review highlights representative natural antibacterial surfaces and discusses their corresponding mechanisms, including repelling adherent bacteria through tailoring surface wettability and mechanically killing bacteria via engineering surface textures. Following this, we present the recent progress in bioinspired active and passive antibacterial strategies. Finally, the biomedical applications and the prospects of these antibacterial surfaces are discussed.
