Current Oncology (Mar 2024)

Large Language Models in Oncology: Revolution or Cause for Concern?

  • Aydin Caglayan,
  • Wojciech Slusarczyk,
  • Rukhshana Dina Rabbani,
  • Aruni Ghose,
  • Vasileios Papadopoulos,
  • Stergios Boussios

DOI
https://doi.org/10.3390/curroncol31040137
Journal volume & issue
Vol. 31, no. 4
pp. 1817 – 1830

Abstract

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The technological capability of artificial intelligence (AI) continues to advance with great strength. Recently, the release of large language models has taken the world by storm with concurrent excitement and concern. As a consequence of their impressive ability and versatility, their provide a potential opportunity for implementation in oncology. Areas of possible application include supporting clinical decision making, education, and contributing to cancer research. Despite the promises that these novel systems can offer, several limitations and barriers challenge their implementation. It is imperative that concerns, such as accountability, data inaccuracy, and data protection, are addressed prior to their integration in oncology. As the progression of artificial intelligence systems continues, new ethical and practical dilemmas will also be approached; thus, the evaluation of these limitations and concerns will be dynamic in nature. This review offers a comprehensive overview of the potential application of large language models in oncology, as well as concerns surrounding their implementation in cancer care.

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