International Journal of Infectious Diseases (Dec 2020)
SARS-CoV-2 infection does not induce HIV viral escape in the central nervous system: A case series
- C. Pinnetti,
- A. Vergori,
- C. Agrati,
- C. Castilletti,
- P. Campioni,
- R. Gagliardini,
- A. Mondi,
- S. Notari,
- A. Amendola,
- S. Cicalini,
- F. Baldini,
- M.R. Capobianchi,
- A. Antinori
Affiliations
- C. Pinnetti
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy; Corresponding authors at: National Institute for Infectious Disease “L. Spallanzani”, Via Portuense 292, 00149, Rome, Italy.
- A. Vergori
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy; Corresponding authors at: National Institute for Infectious Disease “L. Spallanzani”, Via Portuense 292, 00149, Rome, Italy.
- C. Agrati
- Cellular Immunology and Pharmacology Laboratory, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- C. Castilletti
- Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- P. Campioni
- Radiology Unit, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, Italy
- R. Gagliardini
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- A. Mondi
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- S. Notari
- Cellular Immunology and Pharmacology Laboratory, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- A. Amendola
- Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- S. Cicalini
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- F. Baldini
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- M.R. Capobianchi
- Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- A. Antinori
- HIV/AIDS Unit, National Institute for Infectious Diseases, Lazzaro Spallanzani IRCCS, Rome, Italy
- Journal volume & issue
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Vol. 101
pp. 38 – 41
Abstract
We report two cases of HIV positive patients with SARS-CoV-2 infection and a recent diagnosis of opportunistic infections of central nervous system (CNS). We investigated the potential impact of coinfection with SARS-CoV-2 on HIV replication in CNS.