Respirology Case Reports (Jul 2024)

Lymphoid follicular hyperplasia arising from the chest wall presenting as a substantial mass

  • Naoya Kitamura,
  • Keitaro Tanabe,
  • Toshihiro Ojima,
  • Koichiro Shimoyama,
  • Akira Noguchi,
  • Kenichi Hirabayashi,
  • Tomoshi Tsuchiya

DOI
https://doi.org/10.1002/rcr2.1417
Journal volume & issue
Vol. 12, no. 7
pp. n/a – n/a

Abstract

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Abstract Lymphoid follicular hyperplasia (LFH) is a benign lymphoproliferative disease. Although it can occur within the thoracic cavity, LFH originating from the chest wall has not been reported. A 79‐year‐old woman was incidentally found to have a well‐defined mass on the left posterior chest wall during a preoperative examination for aortic valve replacement. The mass had slowly grown over 6 years. Thoracoscopic surgical resection was performed without complications. Pathological examination ruled out lymphoproliferative diseases, such as Castleman disease or malignant lymphoma, and a diagnosis of LFH was made. Although LFH generally has a good prognosis, surgical resection is recommended for diagnostic and therapeutic purposes owing to the possibility of malignancy masquerading as a reactive lesion. This is the first report of an LFH arising from the chest wall with imaging findings similar to other benign tumours. Its potential as a differential diagnosis for tumours with similar imaging findings is highlighted.

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