Dopamine-Serotonin Transporter Disease

Abstract

Investigators at the Hospital for Sick Children, University of Toronto, Canada report 8 children of a consanguineous Saudi Arabian family who had a similar movement disorder, with autosomal recessive inheritance and a mutation in the SLC18A2 gene that encodes vesicular monoamine transporter 2 [VMAT2].

Keywords

• norepinephrine
• neurologic examination
• dopamine agonists