Hidradenitis Suppurativa Prevalence by Age and Race in the United States

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurring painful nodules, abscesses, and sinus tracts in apocrine gland-rich areas. The demographics of HS are not well-established in the United States. Purpose: The purpose of this study was to investigate the HS rate by demographics using the All of Us open-access database initiative from the National Institutes of Health in the United States. Methods: A cross-sectional statistical analysis of patients diagnosed with HS (ICD-10-CM code L73.2) in the All of Us open-access database was performed. Prevalence rates were calculated using Wald’s method with 95% confidence intervals (CIs). Results: Among 407,333 participants, 1616 cases of HS were identified, representing an overall prevalence of 0.40% (95% CI, 0.38–0.42) with a 4:1 female-to-male ratio. The prevalence varied among racial groups: 0.28% in Whites, 0.76% in Blacks, 0.37% in Hispanics, and 0.10% in Asians. The 18–25 age group showed the highest prevalence at 1.70% (95% CI, 1.46–2.00), with a steady decrease in older age groups. Conclusion: Women, Blacks, and younger people (18–25) have a higher prevalence of HS.

Keywords

• age
• all of us database
• demographics
• hidradenitis suppurativa
• prevalence
• race