Nature Communications (Feb 2023)
Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats
- Miguel Angel Brieño-Enríquez,
- Mariela Faykoo-Martinez,
- Meagan Goben,
- Jennifer K. Grenier,
- Ashley McGrath,
- Alexandra M. Prado,
- Jacob Sinopoli,
- Kate Wagner,
- Patrick T. Walsh,
- Samia H. Lopa,
- Diana J. Laird,
- Paula E. Cohen,
- Michael D. Wilson,
- Melissa M. Holmes,
- Ned J. Place
Affiliations
- Miguel Angel Brieño-Enríquez
- Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh
- Mariela Faykoo-Martinez
- Department of Cell and Systems Biology, University of Toronto
- Meagan Goben
- Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh
- Jennifer K. Grenier
- RNA sequencing core and Center for Reproductive Genomics, College of Veterinary, Cornell University
- Ashley McGrath
- Department of Population Medicine & Diagnostic Sciences, Cornell University
- Alexandra M. Prado
- Department of Population Medicine & Diagnostic Sciences, Cornell University
- Jacob Sinopoli
- Department of Population Medicine & Diagnostic Sciences, Cornell University
- Kate Wagner
- Department of Population Medicine & Diagnostic Sciences, Cornell University
- Patrick T. Walsh
- Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh
- Samia H. Lopa
- Magee-Womens Research Institute, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh
- Diana J. Laird
- Department of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco
- Paula E. Cohen
- Center for Reproductive Genomics, Department of Biomedical Sciences, Cornell University
- Michael D. Wilson
- Program in Genetics and Genome Biology, The Hospital for Sick Children
- Melissa M. Holmes
- Department of Cell and Systems Biology, University of Toronto
- Ned J. Place
- Department of Population Medicine & Diagnostic Sciences, Cornell University
- DOI
- https://doi.org/10.1038/s41467-023-36284-8
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 17
Abstract
Female naked mole rats are long lived and show little or no decline in fertility over their lifespan. Here Brieño-Enríquez et al., demonstrate that naked mole-rats establish an exceptionally large ovarian reserve and undergo postnatal oogenesis.
