PLoS ONE (Jan 2021)

COVID-19: Post-recovery long-term symptoms among patients in Saudi Arabia.

  • Mostafa M Khodeir,
  • Hassan A Shabana,
  • Zafar Rasheed,
  • Abdullah S Alkhamiss,
  • Mohamed Khodeir,
  • Mohammad S Alkhowailed,
  • Sami Alharbi,
  • Mansour Alsoghair,
  • Suliman A Alsagaby,
  • Waleed Al Abdulmonem

DOI
https://doi.org/10.1371/journal.pone.0260259
Journal volume & issue
Vol. 16, no. 12
p. e0260259

Abstract

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BackgroundAfter recovery from acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many patients experience long-term symptoms in different body systems. The aim of the present study was to identify these symptoms, their severity, and their duration as a first step in building a system to classify post-recovery long-term symptoms of coronavirus disease 2019 (COVID-19).MethodsAn online-based cross-sectional survey was administered between September and October 2020. Data regarding the severity of post-recovery symptoms and their duration were collected using an Arabic questionnaire divided into six categories encompassing the 20 most prevalent symptoms.ResultsA total of 979 patients recovered from COVID-19 in Saudi Arabia in the study period, of whom 53% were male and 47% were female. The most common symptoms included general fatigue and weakness (73% each), with moderate severity of neurological symptoms including mood changes (41%) and insomnia (39%). Among the special senses, loss of smell and taste of marked severity were reported by 64% and 55% among respiratory symptoms, cough of mild severity (47%), and dyspnea of moderate severity (43%). Loss of appetite of moderate severity was reported in 42%, and diarrhea, abdominal pain, and nausea of mild severity were reported by 53%, 50%, and 44% of respondents, respectively.ConclusionsLong-term symptoms after recovery from COVID-19 warrant patient follow-up. The authors propose a classification system as a starting point to guide the identification and follow-up of long-term symptoms post-recovery, and recommend larger-scale studies to broaden the definition of recovery from COVID-19, which appears to have two phases, acute and chronic.