Nature Communications (May 2018)

Photonic force optical coherence elastography for three-dimensional mechanical microscopy

  • Nichaluk Leartprapun,
  • Rishyashring R. Iyer,
  • Gavrielle R. Untracht,
  • Jeffrey A. Mulligan,
  • Steven G. Adie

DOI
https://doi.org/10.1038/s41467-018-04357-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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Optical tweezers, while well suited for micro-manipulation, are difficult to apply to volumetric microrheology. Here, Leartprapun et al. combine low-NA optical radiation-pressure forces with sensitive interferometric detection to enable volumetric microrheology with promising applications in biological systems.