Case Reports in Oncology (Dec 2009)

Darier-Roussy Sarcoidosis Mimicking Metastatic Breast Cancer

  • Lokesh Viswanath,
  • Siddanna Pallade,
  • B. Krishnamurthy,
  • T. Naveen,
  • B.L. Preethi,
  • K.P.R. Pramod,
  • Obula Reddy,
  • G. Padma

DOI
https://doi.org/10.1159/000262412
Journal volume & issue
Vol. 2, no. 3
pp. 251 – 254

Abstract

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Subcutaneous sarcoidosis (also known as ‘Darier-Roussy sarcoid’) is a cutaneous condition characterized by numerous deep-seated nodules on the trunk and extremities. Coexistence of sarcoidosis and breast cancer are reported in the literature, but there will always be a chance of misdiagnosis. It is very crucial to obtain a tissue diagnosis of suspicious metastatic lesions. We report a case of breast cancer presenting with a subcutaneous sarcoid lesion masquerading as a metastatic lesion. A 50-year-old female patient, who had had cancer of the left breast, was on hormone therapy 2 years after treatment with surgery, radiotherapy and chemotherapy. The patient presented with a sudden onset of a forehead subcutaneous swelling mimicking metastasis which on excision biopsy was proved to be sarcoidosis. In India, sarcoidosis is reported rarely. We have to keep in mind that there is a chance of the metastatic lesions being of sarcoidosis origin or another granulomatous disease. To avoid misdiagnosis, it is better to obtain a tissue diagnosis.

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