TTYH family members form tetrameric complexes at the cell membrane

Emelia Melvin; Zuzana Kalaninová; Elia Shlush; Petr Man; Moshe Giladi; Yoni Haitin

doi:10.1038/s42003-022-03862-3

Communications Biology (Aug 2022)

TTYH family members form tetrameric complexes at the cell membrane

Emelia Melvin,
Zuzana Kalaninová,
Elia Shlush,
Petr Man,
Moshe Giladi,
Yoni Haitin

Affiliations

Emelia Melvin: Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University
Zuzana Kalaninová: Institute of Microbiology of the Czech Academy of Sciences, Division BioCeV, Prumyslova 595
Elia Shlush: Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University
Petr Man: Institute of Microbiology of the Czech Academy of Sciences, Division BioCeV, Prumyslova 595
Moshe Giladi: Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University
Yoni Haitin: Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University

DOI: https://doi.org/10.1038/s42003-022-03862-3
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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Single-molecule microscopy and in situ cross-linking show that the conserved Tweety homolog (TTYH) proteins have an innate tetrameric organization at the cell membrane.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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