Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer

• J. Kaur,
• M. Adhikari,
• H.M. Sabol,
• A. Anloague,
• S. Khan,
• L. Barnes,
• J.B. Stambough,
• M. Palmieri,
• O. ReyesCastro,
• E. Ambrogini,
• M. Almeida,
• C.A. O'Brien,
• I. Nookaew,
• J. Delgado-Calle

Affiliations

J. Kaur

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

M. Adhikari

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

H.M. Sabol

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

A. Anloague

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

S. Khan

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

L. Barnes

Department of Orthopedic Surgery; University of Arkansas for Medical Sciences, Little Rock, AR, USA

J.B. Stambough

Department of Orthopedic Surgery; University of Arkansas for Medical Sciences, Little Rock, AR, USA

M. Palmieri

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases and Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA

O. ReyesCastro

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases and Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA

E. Ambrogini

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases and Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA

M. Almeida

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases and Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA

C.A. O'Brien

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases and Center for Musculoskeletal Disease Research, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA

I. Nookaew

Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA

J. Delgado-Calle

Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA