Translational Neuroscience (Mar 2021)

Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)

  • Li Xin,
  • Qian Yan,
  • Tang Kaihua,
  • Li Yang,
  • Tao Rui,
  • Gong Chunyan,
  • Huang Li,
  • Zou Kaiwen,
  • Liu Lindong

DOI
https://doi.org/10.1515/tnsci-2021-0013
Journal volume & issue
Vol. 12, no. 1
pp. 103 – 113

Abstract

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Spinal cord injury (SCI) is the most serious complication of spinal injury, often leading to severe dysfunction of the limbs below the injured segment. Conventional therapy approaches are becoming less and less effective, and gene therapy is a new research direction by now.

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