Candidate processes for autism spectrum disorders revealed by copy number variation analysis

Abstract

Despite the large number of candidate genes for mental disorders, molecular mechanisms of the majority remain unknown. To fill this gap, we have studied genomic networks-candidates (instead of genes) in a group of children with brain disorders. The identification of such processes seems to be more promising for developing therapeutic strategies in contrast to candidate gene identification.

Keywords

• intellectual disability, autism, mental illness, molecular mechanisms, genomic networks, candidate genes, genome