Breast Cancer and Microbiota: A Literature Review

Abstract

Breast Cancer is the most frequent type of cancer in women. It is the second greatest cause of cancer-related deaths among women in high-income countries. The objective of this current review is to elucidate the role of gut microbiota in cancer in general, with a specific focus on breast cancer. The dysbiosis of gut microbiota is a crucial component that has recently come to light, possibly altering the development, treatment, and prognosis of breast cancer through numerous molecular pathways. This review study investigates the relationships between gut microbiota and breast cancer, with an emphasis on how gut microbiota impacts the microenvironment of breast cancer. Final views on improving breast cancer prognosis and risk assessment may be influenced by new data from clinical trials on the breast-microbiome axis and the ability of immunotherapy to modify the microbiome associated with breast cancer.

Keywords

• breast cancer
• cancer therapeutics
• metabolomics
• microbiota