Journal of Microbiology, Immunology and Infection (Dec 2021)

Streptococcus gallolyticus – A potentially neglected pathogen causing neonatal sepsis not covered by routine group B streptococcus screening

  • Jun Yi Sim,
  • Lan-Wan Wang,
  • Julie Chi Chow,
  • Wei-Yun Hsu,
  • Yu-Chin Chen,
  • Yi-Hsin Chang,
  • Yun Chou,
  • Wei-Yu Chen,
  • Hung-Jen Tang,
  • Tu-Hsuan Chang

Journal volume & issue
Vol. 54, no. 6
pp. 1190 – 1192

Abstract

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We report 4 cases of neonatal sepsis caused by Streptococcus gallolyticus. The clinical course was quite similar to early-and late-onset group B streptococcus disease. None of the mothers had group B streptococcus (GBS) colonization on prenatal screening nor received intrapartum antibiotics. We proposed the sporadic distribution of S. gallolyticus sepsis among neonates was partly due to relatively low colonization rate in adults compared with GBS. Species determination of S. gallolyticus may not be available using conventional microbiological methods and may contribute to underestimation or misclassification. In our series, we highlighted the importance of S. gallolyticus as an important pathogen in neonatal sepsis deserving further surveillance.

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