Communications Biology (Mar 2022)

Pleiotropic actions of phenothiazine drugs are detrimental to Gram-negative bacterial persister cells

  • Sayed Golam Mohiuddin,
  • Thao Vy Nguyen,
  • Mehmet A. Orman

DOI
https://doi.org/10.1038/s42003-022-03172-8
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 15

Abstract

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Phenothiazines, which have previously been approved as antipsychotic drugs, can also reduce growth and metabolism in a range of Gram-negative bacterial pathogens.