Diagnostic value of colposcopy and histopathology in patients with abnormal Pap smear and suspicious clinical findings referring to Sanandaj Besat Hospital in 2012-2014

Abstract

Introduction: Cervical cancer is one of the main causes of women's mortality in many of developing world countries and had a significant increase in recent years. Using appropriate screening methods, this disease can be diagnosed at early stages and the deaths caused by it will be reduced. This study was performed with aim to compare the results of colposcopy and histology in patients with abnormal Pap smear or suspicious clinical findings. Methods: This cross-sectional analytic study was performed on 75 patients who had referred to Besat Hospital in Sanandaj from January 2013 to January 2016 with abnormal Pap smear and suspicious clinical findings in order to perform colposcopy and Pap smear. Colposcopic results and histological findings were extracted from the patients' files. Data were analyzed using SPSS software (version 22) and Chi-square test. The confidence intervals for diagnostic value indices were 0.05. Results: Histopathology and colposcopy studies were conducted on 36 patients with abnormal Pap smear and 39 patients with suspicious symptoms and clinical findings. Sensitivity and specificity of colposcopy were 69.23% and 73.46%, respectively. The positive and negative predictive values of colposcopy were 58.07% and 81.82%, respectively. There was significant relationship between the results of colposcopy and histology. Conclusion: In cases of abnormal Pap smear and suspicious clinical findings, colposcopy can be used to validate the findings.

Keywords

• cervical cancer
• colposcopy
• histopathology
• pap smear