Chronic Wound Care Management and Research (Nov 2022)

Meeting the Challenges in Pediatric Wound Care: Our 15-Year Experience with Dialkylcarbamoyl Chloride-Coated Dressing Technology in Acute and Chronic Wounds

  • Ciprandi G,
  • Crucianelli S,
  • Grussu F,
  • Spuntarelli G,
  • Marino SFM,
  • Urbani U,
  • Bernaschi P,
  • Sisto A,
  • Rizzo MI,
  • Zama M

Journal volume & issue
Vol. Volume 9
pp. 23 – 33

Abstract

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Guido Ciprandi,1,2 Serena Crucianelli,2 Francesca Grussu,2 Giorgio Spuntarelli,2 Simone Faustino Maria Marino,2 Urbano Urbani,2 Paola Bernaschi,3 Annamaria Sisto,3 Maria Ida Rizzo,2 Mario Zama4 1Chief Pediatric Wound Care High Specialization, Plastic and Maxillofacial Surgery Unit, Bambino Gesu’ Children’s Hospital, Research Institute, Rome, Italy; 2Consultant, Plastic and Maxillofacial Surgery Unit, Bambino Gesù Children’s Hospital, Research Institute, Rome, Italy; 3Microbiology Unit, Bambino Gesu’ Children’s Hospital, Research Institute, Rome, Italy; 4Head, Plastic and Maxillofacial Surgery Unit, Bambino Gesù Children’s Hospital, Research Institute, Rome, ItalyCorrespondence: Guido Ciprandi, via Arturo Colautti, 5, Rome, 00152, Italy, Tel +39.3389400595, Fax +39.06.69592115, Email [email protected]; [email protected]: Although similar in structure, pediatric skin is more delicate and vulnerable compared with adult skin and, as a result, is more prone to wounding. The immune response in pediatric skin is underdeveloped because of immature inflammatory cells and lower number of bone marrow progenitor cells. Therefore, pediatric patients, particularly newborns, have weak responses to microorganisms. The use of antimicrobial agents (eg, antibiotics, antimicrobial wound dressings, etc.) to aid in the prevention and/or treatment of wounds prone to or which are infected is one treatment option. Antimicrobial wound dressings using DACC technology physically bind bacteria and reduce the need for chemically active antimicrobial agents. This perspective is intended to highlight the benefit of DACC technology wound dressings for the prevention and treatment of pediatric wounds related to wound infection. We have found that DACC technology dressings are of benefit in the treatment of pediatric wounds and offer a significant resource for the treatment of pediatric wounds.Keywords: pediatric wounds, infection, DACC technology

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