Nature Communications (Jun 2021)

Heteromeric HSFA2/HSFA3 complexes drive transcriptional memory after heat stress in Arabidopsis

  • Thomas Friedrich,
  • Vicky Oberkofler,
  • Inês Trindade,
  • Simone Altmann,
  • Krzysztof Brzezinka,
  • Jörn Lämke,
  • Michal Gorka,
  • Christian Kappel,
  • Ewelina Sokolowska,
  • Aleksandra Skirycz,
  • Alexander Graf,
  • Isabel Bäurle

DOI
https://doi.org/10.1038/s41467-021-23786-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Moderate heat stress primes plants to acquire tolerance to subsequent, more severe heat stress. Here the authors show that the HSFA3 transcription factor forms a heteromeric complex with HSFA2 to sustain activated transcription of genes required for acquired thermotolerance by promoting H3K4 hyper-methylation.