Scientific Reports (May 2018)

Survey of Antithrombotic Treatment in Rural Patients (>60 years) with Atrial Fibrillation in East China

  • Yong Wei,
  • Juan Xu,
  • Haiqing Wu,
  • Genqing Zhou,
  • Songwen Chen,
  • Caihong Wang,
  • Yahong Shen,
  • Shunhong Yang,
  • Bin Wang,
  • Zheng He,
  • Jianping Sun,
  • Weidong Sun,
  • Ping Ouyang,
  • Shaowen Liu

DOI
https://doi.org/10.1038/s41598-018-24878-y
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 8

Abstract

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Abstract The prevalence and antithrombotic treatment of atrial fibrillation (AF) in Chinese rural population is not well known. The aim of this study was to investigate the extent to which antithrombotic treatment was prescribed for rural AF patients >60 years. We identified 828 AF patients from 36734 rural residents >60 years in Shanghai China. Our data indicated the overall prevalence rate of AF was 2.3% in rural population >60 years in East China and 38.9% of AF patients underwent antithrombotic therapy, including warfarin (5.9%), aspirin (29.6%), clopidogrel (2.9%) and aspirin combined with clopidogrel (0.5%). Of enrolled subjects, 98.4% had CHA2DS2-VASc score ≥1, 72.0% had HAS-BLED score <3 and 59.2% had CHA2DS2-VASc score ≥2 with HAS-BLED score <3. Missing early detection (34.9%), delay in seeking treatment for asymptomatic AF (25.5%) and doctors’s incomplete inform of AF-related risk of stroke to patients (21.7%) were three dominant causes for failing anticoagulant usage. In conclusion, most AF patients were with a high risk of thrombosis and a low risk of bleeding in China, but a large majority of them failed to take anticoagulants mainly for missing an early screening of AF and lack of awareness on AF for both patients and primary care physicians.