Nature Communications (Nov 2018)

Programming molecular topologies from single-stranded nucleic acids

  • Xiaodong Qi,
  • Fei Zhang,
  • Zhaoming Su,
  • Shuoxing Jiang,
  • Dongran Han,
  • Baoquan Ding,
  • Yan Liu,
  • Wah Chiu,
  • Peng Yin,
  • Hao Yan

DOI
https://doi.org/10.1038/s41467-018-07039-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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Designing nucleic acid-based nanostructures with knots remains challenging. Here the authors present a general strategy to design and construct highly knotted 2D and 3D nanostructures from single-stranded DNA or RNA