Single-breath-hold photoacoustic computed tomography of the breast

Li Lin; Peng Hu; Junhui Shi; Catherine M. Appleton; Konstantin Maslov; Lei Li; Ruiying Zhang; Lihong V. Wang

doi:10.1038/s41467-018-04576-z

Nature Communications (Jun 2018)

Single-breath-hold photoacoustic computed tomography of the breast

Li Lin,
Peng Hu,
Junhui Shi,
Catherine M. Appleton,
Konstantin Maslov,
Lei Li,
Ruiying Zhang,
Lihong V. Wang

Affiliations

Li Lin: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology
Peng Hu: Department of Biomedical Engineering, Washington University in St. Louis, One Brookings Dr.
Junhui Shi: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology
Catherine M. Appleton: Breast Imaging Section, Washington University School of Medicine in St. Louis
Konstantin Maslov: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology
Lei Li: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology
Ruiying Zhang: Department of Biomedical Engineering, Washington University in St. Louis, One Brookings Dr.
Lihong V. Wang: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology

DOI: https://doi.org/10.1038/s41467-018-04576-z
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 9

Abstract

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The current standard for breast cancer diagnostic is a mammogram; however, the sensitivity of mammography can be low in radiographically dense breasts. Here the authors develop a single-breath-hold photoacoustic computed tomography (SBH-PACT) system to reveal detailed angiographic structures in human breasts allowing the detection of higher blood vessel densities associated with tumors.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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