A case of carcinoma of the oral floor treated successfully with the TPS therapy as an induction chemotherapy

Abstract

In late years, combination of Cisplatin and Docetaxel, S-1 (as follows: a TPS therapy) show a high effect in induction chemotherapy in the oral carcinoma, we are said to be it, and it is used. We receive TPS therapy for carcinoma in the oral floor (T2N2bM0) this time and report our experience with the case that had a complete response. 61-years-old men, with squamous cell carcinoma in the Left oral floor (T2N2bM0) was diagnosed than a clinical examination and image findings, an examination of histopathology. Because it was local progressive carcinoma, perform induction chemotherapy in a TPS therapy preoperative tumor reduction. The primary tumor, the cervical metastasis lymph nodes reduced after 1 course end remarkably. We performed floor of mouth part tumor resection and all left neck dissection. The histologic effect of treatment judgment were Grade3 for histopathology. Resist evaluation was CR. We follow it up, but it is primary and the cervical lymph nodes recurrence does not show it now either.

Keywords

• TPS therapy
• Induction chemotherapy
• Oral carcinoma
• Local progressive carcinoma
• Histopathology