Additional New Minor Cucurbitane Glycosides from Siraitia grosvenorii

Abstract

Continuous phytochemical studies of the crude extract of Luo Han Guo (Siraitia grosvenorii) furnished three additional new cucurbitane triterpene glycosides, namely 11-deoxymogroside V, 11-deoxyisomogroside V, and 11-deoxymogroside VI. The structures of all the isolated compounds were characterized on the basis of extensive NMR and mass spectral data as well as hydrolysis studies. The complete 1H- and 13C-NMR spectral assignments of the three unknown compounds are reported for the first time based on COSY, TOCSY, HSQC, and HMBC spectroscopic data.

Keywords

• Siraitia grosvenorii
• curcubitaceae
• Luo Han Guo
• curcubitane glycosides
• structure elucidation
• NMR
• MS