Comparison of ALitretinoin with PUVA as the first-line treatment in patients with severe chronic HAnd eczema (ALPHA): study protocol for a randomised controlled trial

• Catherine Smith,
• Miriam Wittmann,
• Fiona Cowdell,
• Sarah Brown,
• Catherine Reynolds,
• Catherine Fernandez,
• Sandy Tubeuf,
• Jane Nixon,
• Rachael Gilberts,
• Mark Goodfield,
• Isabelle L Smith,
• John T Lear,
• Lesley Sunderland,
• Cathy Green,
• Philip Hampton,
• Amy Barker,
• Armando Vargas-Palacios

Affiliations

Catherine Smith

St John`s Institute of Dermatology, Guy’s & St Thomas’s NHS Foundation Trust, London, UK

Miriam Wittmann

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK

Fiona Cowdell

Faculty of Health Education and Life Sciences, Birmingham City University, Birmingham, UK

Sarah Brown

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

Catherine Reynolds

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

Catherine Fernandez

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

Sandy Tubeuf

Institute of Health and Society, Faculté de Santé Publique, Clos Chapelle-aux-Champs, Brussels, Belgium

Jane Nixon

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

Rachael Gilberts

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

Mark Goodfield

Department of Dermatology, Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK

Isabelle L Smith

Clinical Trials Research Unit, Leeds Institute for Clinical Trials Research, University of Leeds, Leeds, UK

John T Lear

Department of Dermatology, Salford Royal NHS Foundation Trust, Manchester, UK

Lesley Sunderland

Street Lane Medical Practice, Leeds, UK

Cathy Green

Department of Dermatology, Ninewells Hospital, Dundee, UK

Philip Hampton

Department of Dermatology, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK

Amy Barker

Faculty of Biological Sciences, University of Leeds, Leeds, UK

Armando Vargas-Palacios

Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK