Pleural involvement of diffuse large B-cell lymphoma mimicking malignant pleural mesothelioma

Takanori Ito; Kohei Fujita; Misato Okamura; Yoshiaki Okuno; Zentaro Saito; Osamu Kanai; Koichi Nakatani; Koki Moriyoshi; Tadashi Mio

doi:10.1016/j.rmcr.2020.101206

Respiratory Medicine Case Reports (Jan 2020)

Pleural involvement of diffuse large B-cell lymphoma mimicking malignant pleural mesothelioma

Takanori Ito,
Kohei Fujita,
Misato Okamura,
Yoshiaki Okuno,
Zentaro Saito,
Osamu Kanai,
Koichi Nakatani,
Koki Moriyoshi,
Tadashi Mio

Affiliations

Takanori Ito: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Kohei Fujita: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan; Corresponding author. Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, 1Fukakusa-Mukaihata, Fushimi-Ku, Kyoto 612-8555, Japan.
Misato Okamura: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Yoshiaki Okuno: Department of Haematology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Zentaro Saito: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Osamu Kanai: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Koichi Nakatani: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Koki Moriyoshi: Department of Diagnostic Pathology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
Tadashi Mio: Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan

DOI: https://doi.org/10.1016/j.rmcr.2020.101206
Journal volume & issue: Vol. 31
p. 101206

Abstract

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Diffuse large B-cell lymphoma (DLBCL) is a common cancer in haematology. We report a case of DLBCL mimicking malignant pleural mesothelioma (MPM). A 75-year-old man with a 1-week exacerbation of dyspnoea on exertion and right pleural effusion on chest radiography was admitted to our hospital. Positron emission tomography/computed tomography revealed diffuse pleural thick lesions and massive pleural effusion, and these lesions had accumulation of fluorodeoxyglucose. Because we suspected MPM or lung cancer, we performed a biopsy with thoracoscopy to confirm the diagnosis. A biopsy of the pleural effusion with thoracoscopy revealed DLBCL. Chemotherapy was immediately selected, and the diffuse thickened pleural wall and massive pleural effusion of the right chest were significantly improved after two cycles of chemotherapy.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://www.sciencedirect.com/journal/respiratory-medicine-case-reports

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